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Everything you need to know about stem cell treatments and their role in the future of healthcare and regenerative medicine.

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News, opinion and advice on stem cell research and treatment, from Wideacademy.

Feature

Refractory anaemia with excess blasts and treatment using stem cell therapies

What is Refractory Anaemia with Excess Blasts? Refractory anaemia with excess blasts (RAEB), also known as myelodysplastic syndrome with excess blasts (MDS-EB), is a cancer of the blood and bone marrow, characterised by defective formation of all three types of blood cell. The bone marrow cells are abnormal (dysplastic) and immature, meaning that they have difficulty making new blood cells. Red blood cells, white blood cells and platelets are all affected. As defective cells tend to die earlier than normal cells, the patient has too few circulating normal blood cells. Patients with MDS-EB…

Peripheral blood stem cells

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Second Opinion

"A new milestone in laboratory grown human brain tissue" (WorldHealth.net )

What do our experts say?

WideCells CSO Peter Hollands looks at how stem cells are helping to power the next generation of disease study: Quite a step forward here for the development of treatments of diseases caused by defects relating to myelin, a substance which forms the insulation of the brain. Among other things, this includes multiple sclerosis. It focuses on an advancement in the generation of organoids…
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Feature

Gene-editing technique CRISPR leads to identification of dangerous breast cancer mutations

Breast cancer type 1 (BRCA1) is a human tumor suppressor gene, found in all humans. Scientists have been using CRISPR genome editing to deliberately engineer some 4,000 different variants of the BRCA1 gene in human cells, as Jay Shendure , Greg Findlay , and Lea Starita , of the University of Washington , report:

Research 5

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Feature

Bare Lymphocyte Syndrome and the future of treatment using stem cell therapies

What is Bare Lymphocyte Syndrome? Bare Lymphocyte Syndrome is a rare, severe combined immunodeficiency disease (SCID). People with the condition suffer from frequent and severe bacterial, viral or fungal infections which can result in complications or may even be fatal. Bare Lymphocyte Syndrome is a deficiency in a part of the immune system that helps the body identity and fight infections, called major histocompatibility complex (MHC) class I and class II proteins. Severe combined immunodeficiency diseases are a group of primary immunodeficiencies, each with its own specific genetic cause…

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Second Opinion

"Experts warn on proliferation of dubious stem cell clinics" (Financial Times)

What do our experts say?

New US legislation means it will be easier for Americans to undergo experimental treatments – but, as WideCells CSO Peter Hollands warns, the risks are significant: New US legislation titled the ‘Right to Try’ means that seriously ill patients will have greater access to experimental treatments. At first blush, this might seem like a good idea – but there is the potential for it to cause serious…
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Feature

Acute Myelofibrosis and stem cell treatment for rare bone marrow cancer

What is Acute Myelofibrosis? Acute Myelofibrosis is a rare form of bone marrow cancer. It occurs as a result of bone marrow cells functioning in an abnormal way. The disease is characterised by a build-up of collagen in the bone marrow, which causes scar tissue to form (fibrosis) and results in bone marrow failure. Scarring inhibits healthy blood production in the bone marrow, which leads to too few red blood cells, white blood cells and platelets being produced (pancytopenia). This can lead organs other than the bone marrow, forming blood cells to compensate for the shortage, known as…

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